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dabble1980 Profile
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Ex96

Registered: 12-2012
Posts: 995
Karma: 7 (+7/-0)
Cholesterol Deficiency Haplotype


Holstein Haplotype for Cholesterol Deficiency (HCD) is becoming a growing concern in the world for Holstein breeders. Calves born with this deficiency either show the symptoms right away and die or can live a slightly longer period and die eventually from the effects of this Haplotype. The source of this haplotype has been determined to be STORM. Having at least 8 calves die from what was originally an undiagnosed condition, I can now suspect this to be the cause. This issue is growing

Genex has apparently culled any sire in the lineup with this haplotype or with pedigree history of the haplotype.

Any carrier-bull searched on the Accelerated database is listed as carrier under the designation HCD1.

Select Sire's new sire pamphlet has 1 page listing the sires who are carriers but there has been no designation or listing posted to their website. Select posted a PDF to their website in 2014 but there is no formal notification on individual bull pages

- A good amount of Red Sires are carriers

Goldwyn- Carrier

Atwood and brothers are not carriers (Despite having Goldwyn as a sire (Carrier) and Storm on the maternal side.

Armani- Carrier. Apparently there have been a lot of dead calves from this haplotype from this bull

I am surprised this has not been a greater concern for discussion recently. The research is ongoing but the death rate seems to be increasing as there is no control plan. Genex took the step to cull the affected bulls in their line up, Accelerated took the nomenclature and added it to every bull in their database. Why haven't other studs noted these bulls on their websites, culled them, or made much of any effort to notify breeders.

WHY are studs continuing to offer sires who carry this haplotype or have a pedigree with multiple carriers in it

in 2014 here was the list at Select Sires:
250HO1123 Motivator HCDC
7HO9264 Dempsey HCDC
7HO10848 Grafeeti HCDC
7HO10884 Avery HCDC
7HO11163 Ladd P-Red HCDC
7HO11703 Armani HCDC
7HO12170 Corey HCDC
7HO12580 Bosa HCDC
7HO12626 Manny-Red HCDC
7HO13276 Bowen HCDS

Go to Select Sire's page for Dempsey and there isn't a single mention of this Haplotype being present in this bull.

The complete listing of sires can be found here:
http://www.holsteinusa.com/pdf/haplotype/hapbulcarriers.pdf
10/12/2015, 21:42 Link to this post PM via Email   PM via Forum
 
dabble1980 Profile
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Ex96

Registered: 12-2012
Posts: 995
Karma: 7 (+7/-0)
Re:


Listed below is a small sampling of the accelerated genetic's sires who are positive for the haplotype confirmed in Aug 2015. Since they list it as a "Small Sampling" I do not believe this is all of their carriers

014HO07627 Sanders HCD1
• 014HO07464 Dusk HCD1
• 534HO00032 Kool HCD1
• 534HO00010 Cashcoin HCD1
• 534HO00009 Cashmoney HCD1
• 014HO07449 Ocean Pp HCD1
• 534HO00021 Prodigy-Red HCD1
10/12/2015, 21:57 Link to this post PM via Email   PM via Forum
 
dabble1980 Profile
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Ex96

Registered: 12-2012
Posts: 995
Karma: 7 (+7/-0)
Re:


Searching through Accelerated website, here are carriers:

Draco: Cashcoin x Robust x Planet

Sanders: Halogen x Supersire x Shottbolt

Bowen: Montross x Shamrock x Goldwyn (Suspected Carrier)

Bosa: Jabir x Planet x Shottle


Director: Predestine x Robust x Planet

Vereen: Marso x Supersire x Bookem


Savage *RC: Supershot x Cashcoin

10/12/2015, 22:05 Link to this post PM via Email   PM via Forum
 
dabble1980 Profile
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Ex96

Registered: 12-2012
Posts: 995
Karma: 7 (+7/-0)
Re:


250HO11531 NEWMAN: Robust x Goldwyn x Oman

007HO11430 MCARTHY: Robust x Goldwyn x Prescott

011HO11206 ALTAELLIOT: Bookem x Shottle x Goldwyn

014HO06823 TORPEDO: Shamrock x Freddie x Goldwyn

007HO11619 COLA: Robust x Goldwyn x Oman

001HO10814: Keyboard: Obsever x Goldwyn x ZADE

007HO11763 PREDESTINE: Shamrock x Goldwyn x Outside

200HO02817 LAURENTO: Snowman x Goldwyn x Shottle

029HO16537 CRANDALL: Robust x Alexander x Bolton

029HO16473 VALOR: Beacon x Planet x Goldwyn

10/12/2015, 22:13 Link to this post PM via Email   PM via Forum
 
dabble1980 Profile
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Ex96

Registered: 12-2012
Posts: 995
Karma: 7 (+7/-0)
Re:


September Storm

Comestar Stormatic

Hartline Titanic

TALENT

FINAL CUT

MR BURNS

STALLION

WINDBROOK

LAUTHORITY

STANLEYCUP

LAVANGAURD

ALEXANDER

WINDHAMMER



10/12/2015, 22:19 Link to this post PM via Email   PM via Forum
 
Keff Profile
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EX90

Registered: 11-2014
Posts: 156
Karma: 3 (+4/-1)
Re:


You can go to CDN and click the HCD box https://www.cdn.ca/query/group.php with the other search criteria to narrow your search down. Or when on a individual bull page on CDN just click his pedigree and if it says HCD: 99% he is a carrier
10/12/2015, 22:42 Link to this post PM via Email   PM via Forum
 




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